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胃肠道卵巢转移癌患者人附睾蛋白4的检测及临床意义

Huiping MA,Yaling JIN,Liping YAO, Jie DANG

Chinese Journal of Human Sexuality（2017）

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Abstract
目的:探究胃肠道卵巢转移癌患者人附睾蛋白4(HF4)的水平及临床意义.方法:选择在我院治疗的16例胃肠道卵巢转移癌患者作为观察组.同时选取期间在我院治疗的48例卵巢原发性癌患者为原发组.化学发光免疫分析仪检测两组患者血清HE4、CA125和CEA的浓度水平.结果:原发组血清HE4和CA125水平均显著高于观察组,差异有统计学意义(P＜0.05);此外,观察组中HE4的阳性例数和比例均明显多于CA125(P＜0.05);采用HE4和CEA联合方式在诊断的阳性率方面多于其他两组.结论:HE4作为卵巢癌肿瘤标志物,更适合胃肠道卵巢转移癌患者的诊断检测.临床可采用HE4和CEA联合检测,对于提高胃肠道卵巢转移癌的诊断具有重要的临床价值.
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Key words
Ovarian metastatic cancer with gastrointestinal origin,Human epididymis protein 4,Tumor marker
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