朗格汉斯细胞与尖锐湿疣的发病与复发机制的探讨
Chinese Journal of Human Sexuality(2016)
Abstract
目的:探讨尖锐湿疣(CA)组织中朗格汉斯细胞(LC)的变化.方法:选取尖锐湿疣组30例,正常对照组10例,采用免疫组化法对尖锐湿疣组织和正常组织进行CD1a、S-100蛋白、HLA-DR检测,统计表达阳性的LC数量并观察其形态.结果:尖锐湿疣组织中的CD1a、S-100蛋白、HLA-DR阳性的LC表达均比正常组织降低.复发组与无复发组的表达也有差异.结论:尖锐湿疣组织中存在着LC的缺失和抗原提呈功能异常,这可能与尖锐湿疣的发病与复发有关.
MoreKey words
Condyloma acuminatum (CA),Langerhans cells (LC),CD-1a,S-100,HLA-DR
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