低温等离子接枝改性聚乳酸支架的亲水性

Zhichao MO,Qing LIU,Donglu SHI,Jian ZHAO

Journal of Qingdao University of Science and Technology(Natural Science Edition)（2017）

Cited 2|Views6

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Abstract

聚乳酸具有良好的生物相容性以及可降解性能,但其强疏水性能一定程度上限制了其在可降解支架领域的应用.本研究利用氩气(Ar)低温等离子技术在PDLLA血管支架表面接枝亲水性的聚合物聚乙烯吡咯烷酮(PVP)以及聚醋酸乙烯酯(PVAc).接触角测试表明,经等离子接枝的材料表面接触角由原来的105°~110°可降至22°,由强疏水性变为亲水性.体外细胞粘附性实验表明:等离子处理后的材料表面表现出亲水性质,其细胞的粘附性也得以明显提高,更加有利于细胞在其表面的生长.

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Key words

PDLLA vascular stent,low-temperature plasma grafting,polyvinylpyrrolidone (PVP),polyvinyl acetate (PVAc),hydrophilic,cell adhesion

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