头孢氨苄的k-卡拉胶-壳聚糖-海藻酸钠缓释体系研究
ACTA SCIENTIARUM NATURALIUM UNIVERSITATIS NANKAIENSIS(NATURAL SCIENCE EDITION)（2002）
Abstract
首先以壳聚糖、海藻酸钠为原料制得含头孢氨苄的微囊,再用k-卡拉胶对微囊进行多次包埋,制成缓释体系.测定了其在不同pH值的水溶液中的释药速率,并对包埋次数对释药速率的影响和缓解机理进行了初步讨论.结果表明,该缓释体系的释药时间可达7h,增加包埋次数可延长释药时间.
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