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17α-羟化酶/C17,20-裂解酶(P45017α)抑制剂17-(取代吡唑、异唑基)雄烯衍生物的合成

茹呈杰,雷小平,凌仰之,张礼和

CHEMICAL JOURNAL OF CHINESE UNIVERSITIES（2001）

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Abstract
在17-(3-吡唑基)和17-(5-异唑基)雄甾-4,16-二烯-3-酮的吡唑基的5-位和异唑基的3-位引入取代基, 设计并合成了11个17-(取代的吡唑基、异唑基)雄烯衍生物, 化合物的结构经1H NMR, IR, 元素分析或质谱确证.
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