Search
ChatPaper
AI Writing
analysis
Analysis
编组
Open Data
more
More
RankingsMust ReadingJournal&ConferenceAI TRAI HistoryMaster Reading TreeXiaomai's Star TalentsTrajectoryTalentNDI TrackerAI sign LanguageOpen
VIPCreated with Sketch.

"一锅法"合成对羟基硫代苯甲酰胺

Fang NIE,Xiao-wei ZHANG, Yun-ge LI, Meng CAO,Gang WANG,Fan ZHANG

Chemical Research and Application（2018）

Cited 0|Views3
No score
Abstract
本文采用"一锅法"合成对羟基硫代苯甲酰胺.以对羟基苯甲醛为原料,甲酸为溶剂,氢氧化钠为缚酸剂,与盐酸羟胺反应生成对氰基苯酚.反应完毕后产物不经分离,直接向反应液中加入硫代乙酰胺和浓盐酸继续反应得到对羟基硫代苯甲酰胺,总收率为94.5%(以对羟基苯甲醛计).通过改变盐酸羟胺和氢氧化钠的用量、硫代乙酰胺的用量、浓盐酸的用量以及反应温度,确定了目标化合物的优化制备工艺条件.
More
Translated text
Key words
p-hydroxythiobenzamide,febuxostat,synthetic process
AI Read Science
Must-Reading Tree
Example
Generate MRT to find the research sequence of this paper
Chat Paper
Summary is being generated by the instructions you defined