2-氯-4-苯基喹唑啉的合成

Chinese Journal of Synthetic Chemistry(2018)

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Abstract
以邻苯甲酰苯甲酸为原料,依次经氯代、酰胺化、Hofmann重排、成环及氯化共5步反应合成了2-氯-4-苯基喹唑啉,总收率20.8%,其结构经1H NMR和13C NMR确证.
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Key words
2-benzoylbenzoic acid,2-chloro-4-phenylquinazoline,Hofmann rearrangement,cycliza-tion reaction,synthesis
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