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鼻咽癌放疗后正常显示脑灰质的容积变化 ——基于体素的MR形态学研究

Computerized Tomography Theory and Applications(2017)

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Abstract
目的:探讨鼻咽癌患者放疗后全脑灰质体积的改变情况.方法:对20例接受过放射治疗的鼻咽癌患者及16例已确诊而未行放射治疗的鼻咽癌患者,进行全脑高分辨率T1WI扫描,采用基于体素形态测量学(VBM)方法,分析鼻咽癌治疗组与未治疗组脑灰质体积变化的差异.结果:与未治疗组比较,鼻咽癌治疗组双侧颞中回、左侧额上回、左侧枕下叶脑灰质体积显著减少.结论:鼻咽癌放疗后部分脑区脑灰质体积减少,VBM可早期发现常规MRI未显示的异常.
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Key words
nasopharyngeal carcinoma,brain injury induced by radiation,gray matter
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