Direct comparison of QIAamp DSP Virus Kit and QIAamp Circulating Nucleic Acid Kit regarding cell-free fetal DNA isolation from maternal peripheral blood.
Molecular and Cellular Probes（2019）
Abstract
•Circulating Nucleic Acid Kit is an optimal kit for isolation of cell-free fetal DNA.•DSP Virus kit is suitable for qualitative analysis of cell-free fetal DNA.•Methylation-sensitive restriction helps determine cell-free fetal DNA fraction.•Digital PCR is an accurate method for quantification of cell-free fetal DNA.
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Key words
Cell-free fetal DNA,Digital PCR,DNA isolation,Methylation-sensitive restriction,Prenatal,Fetal DNA fraction
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