替加环素联合头孢哌酮/舒巴坦治疗泛耐药鲍曼不动杆菌的临床疗效评价
Chinese Journal of Microecology(2016)
Abstract
目的 评价替加环素与头孢哌酮/舒巴坦治疗泛耐药鲍曼不动杆菌的临床疗效.方法 重症监护病房(ICU)收治的60例感染泛耐药鲍曼不动杆菌的患者随机分为研究组(n=30)和对照组(n=30),分别给予替加环素+头孢哌酮/舒巴坦和单纯头孢哌酮/舒巴坦治疗,疗程2周.比较两组的临床疗效、细菌清除率、白细胞(WBC)计数、C反应蛋白(CRP)和急性生理与慢性健康评分(APACHEⅡ).结果 研究组总有效率为83.33% (25/30),对照组为50.00% (15/30);研究组细菌清除率为56.67%(17/30),对照组为33.33% (10/30);两组治疗后的APACHEⅡ评分明显增加,WBC计数和CRP都明显降低.治疗后两组三项指标比较差异均具有统计学意义(t=3.852、5.167、4.221,P<0.05).结论 替加环素联合头孢哌酮/舒巴坦治疗泛耐药鲍曼不动杆菌能明显提高临床疗效和细菌清除率,优于单独使用头孢哌酮/舒巴坦.
MoreKey words
Tigecycline,Pan-drug resistance,Acinetobacter baumannii
AI Read Science
Must-Reading Tree
Example
![](https://originalfileserver.aminer.cn/sys/aminer/pubs/mrt_preview.jpeg)
Generate MRT to find the research sequence of this paper
Chat Paper
Summary is being generated by the instructions you defined