血清HBsAg水平与食管胃底静脉曲张破裂出血及child-pugh评分关系研究
International Journal of Virology(2015)
Abstract
目的 对乙肝后肝硬化食管胃底静脉曲张破裂出血及child-pugh评分与血清HBsAg水平的相关性进行分析研究.方法 将82例乙肝后肝硬化患者,根据食管胃底静脉曲张破裂出血情况,分为44例未出血组(未发生食管胃底静脉曲张破裂出血)和38例出血组(发生食管胃底静脉曲张破裂出血).另外根据child-puge分级情况,将患者分为26例child-pugh A级组、33例child-pugh B级组及23例child-pughC级组.分别对各亚组间HBsAg水平含量差异进行对比,并对HBsAg水平与食管胃底静脉曲张破裂出血及child-pugh评分的相关性进行分析.结果 出血组患者血清HBsAg水平含量明显高于未出血组(P<0.05),而child-pugh C级组血清HBsAg水平含量最高(P<0.05),child-pughA级组血清HBsAg水平含量最低(P<0.05).同时血清HBsAg水平与食管胃底静脉曲张破裂出血及child-pugh评分与均存在显著的直线相关性(P<0.05).结论 肝硬化患者血清HBsAg水平与食管胃底静脉曲张破裂出血及child-pugh评分存在密切的相关性.
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Key words
HBsAg,Liver cirrhosis,Esophageal variceal bleeding,Child-Pugh score
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