硝酸舍他康唑的临床应用研究进展
Chinese Journal of Mycology（2015）
Abstract
硝酸舍他康唑(sertaconazole)是一种新型、广谱、高效的外用唑类抗真菌药.本文就其药理作用、抗炎、止痒、抗真菌临床疗效及安全性评价等方面加以综述.新的剂型-微乳凝胶,增强皮肤渗透性和存留时间,而且能减少对皮肤的刺激.外用硝酸舍他康唑治疗皮肤癣菌病和浅表念珠菌感染见效快,治愈率高,疗程短.根据药代动力学,舍他康唑只需每日用药一次,加之其止痒活性,增加了患者依从性,从而提高了临床治愈率.最新临床研究发现外用硝酸舍他康唑乳膏对脂溢性皮炎、特应性皮炎有良好的疗效.
MoreKey words
Sertaconazole nitrate,antifungal,dermatophytoses,superficial candidiasis,seborrheic dermatitis,atopic dermatitis
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