丹皮多糖2b对体外非酶糖化反应及终产物生成的抑制作用
JOURNAL OF BIOLOGY（2005）
Abstract
建立体外非酶糖化系统,即加入200mmol L -1Glc,40g L -1牛血清白蛋白,另加0.01%NaN3抗菌,再加入PSM2b使其终浓度分别为1,0.5,0.1,0.01mg mL-1.37℃保温,温孵2周后测定对非酶糖化反应抑制率(IR1),8周后测定对AGEs产物生成的抑制率(IR2).研究丹皮多糖2b(PSM2b)对体外非酶糖化反应和终产物AGEs的生成均有较高抑制作用.其IR1和IR2最高分别为23.51%和56.51%.PSM2b对非酶糖化引起的糖尿病微血管病变有改善作用.
MoreKey words
Neuroprotective
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