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小鼠免疫相关GTP酶Irgm基因家族的研究进展

Yuxi LIU,Chuanliang LIU,Jinghua WANG

International Journal of Immunology（2016）

Cited 0|Views16
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Abstract
免疫相关GTP酶(IRG)基因家族与抗感染和炎症免疫过程有关.小鼠Irgm1、Irgm2与Ir-gm3基因编码的蛋白参与细胞自噬、Colon氏病等发生发展,并在固有免疫应答中发挥重要作用.了解Irgm1、Irgm2与Irgm3基因的表达、功能等情况以及Irgm1、Irgm2与Irgm3基因编码的蛋白参与免疫过程的机制,有利于免疫系统疾病的治疗.
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Key words
Irgm1,Irgm2,Irgm3,Innate immune response
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