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人类白细胞抗原晶体模型及其在疾病研究中的应用

Wenxuan SUN,Yan XIA,Shuyun ZHANG

International Journal of Immunology（2015）

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Abstract
人类白细胞抗原(HLA)是人类基因组中多态性最高的基因复合体.其编码产物HLA分子具有抗原提呈功能,在机体免疫应答中起到重要作用.大量研究表明,HLA分子与许多自身免疫性疾病和病毒感染性疾病密切相关.深入研究HLA分子与疾病相关性的内在机制将会为人类攻克这些顽疾带来希望.
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Key words
Human leukoeyte antigen molecule,Antigen-binding groove
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