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c-myb转录因子在细胞中作用机制研究进展

Xiao QU,Fang YIN,Huanlong QIN

Chemistry of Life（2019）

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Abstract
转录因子c-myb最初发现与造血器官调控密切相关,且对于多种肿瘤发生发展必不可少,如在乳腺癌、大肠癌等肿瘤中调节细胞增殖、分化.因此,转录因子c-myb被认为是肿瘤治疗潜在靶标.本文综合介绍了c-myb转录因子结构、功能及其在相关肿瘤发生发展中作用以及探索如何进行c-myb靶向治疗.
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