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骨桥蛋白的生物学功能

CHEMISTRY OF LIFE(2001)

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Abstract
骨桥蛋白(Osteopontin,OPN)是一种含精氨酸-甘氨酸-天冬氨酸(Arg-Gly-Asp,RGD)的分泌型糖基化磷蛋白,已归类于细胞外基质(extracellular matrix,ECM)蛋白,曾被称为早期T淋巴细胞活性1(early Tlymphocyte activation 1,Eta-1)、分泌的磷蛋白1(se-crected phosphoprotein 1,SPP-1)、骨唾液酸蛋白1(bone sialoprotein 1,BSP-1)、44kD骨磷蛋白和2αR.
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