虫草素抗肾纤维化研究进展
Chinese Journal of Clinical Healthcare（2019）
Abstract
虫草素是从蛹虫草中分离出的一种核苷类抗生素,具有明显的抗肾纤维化作用.通过对肾纤维化病理机制的研究,阐述虫草素可从细胞分子学水平调控多种细胞因子,从而介导七大信号通路,阻碍其信号传导.七种通路相互关联,从而延缓肾纤维化及慢性肾脏病的进展.
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