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PCR-SSCP 技术快速检测结核分枝杆菌三种基因突变

刘旭红,陈旭庚,张眉眉,苏娅,何雅慧,王莉, 尚艳萍, 吴雪琼,曹立雪

THE JOURNAL OF THE CHINESE ANTITUBERCULOSIS ASSOCIATION（2005）

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Abstract
聚合酶链反应-单链构象多态性(PCR-SSCP)是快速检测基因突变的重要方式之一[1].应用此法对辽宁省90例涂阳患者痰标本分离结核分枝杆菌进行rpoB、rpsL、56例katG基因突变检测,与传统耐药结果比较分析,寻找结核分枝杆菌耐药性与基因突变的关系.
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