应用R软件meta程序包实现遗传关联性研究的Meta分析

Chinese Journal of Evidence-Based Medicine(2017)

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Abstract
单核苷酸多态性与疾病的相关性是遗传关联性研究的典型代表.相对于传统的二分类数据,单核苷酸多态性的数据具有其自身的特点,在开展Meta分析时常使用5种遗传模型.本文通过实例展示如何使用R软件Meta程序包实现单核苷酸多态性数据的Meta分析.
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Key words
R software,Meta package,Genetic association study,Single nucleotide polymorphism,Meta-analysis
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