脑血栓形成患者血清晚期糖基化终末产物变化研究

Chinese Journal of Control of Endemic Diseases(2017)

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Abstract
目的 通过检测血清中晚期糖基化终末产物(Advanced glycation end products,AGEs)的含量,分析AGEs与脑血栓形成患者存在相关性.方法 收集临床病例100例,分为实验组、对照组,实验组为脑血栓形成患者(50例),对照组为同期体检健康者(50例);两组全部采用酶联免疫吸附法(ELISA)测定空腹血清中AEGs的含量,比较实验组与对照组患者AGEs的差别变化.结果 实验组与对照组AGEs水平比较差异具有统计学意义(P<0.01);各组患者的性别、年龄等一般临床资料差异无统计学意义(P>0.05).结论 通过此次研究发现,AGEs的增多与脑血栓形成患者病情的严重程度相关.
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Key words
Advanced glycation end products,Cerebral thrombosis,Enzyme linked immunosorbent assay
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