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Ento-F栓的大鼠阴道黏膜刺激性与豚鼠过敏性实验

Journal of Toxicology(2019)

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Abstract
阴道炎和宫颈炎是常见的女性生殖器官疾病,病因主要与遗传、免疫、机械损伤和菌群失衡有关,主要表现为外阴瘙痒、下腹疼痛、分泌物异常,严重者可引起上生殖器的感染造成宫颈糜烂、盆腔炎和官颈癌等疾病[1-4].目前临床上常用剂型有片剂、胶囊、栓剂、凝胶和洗剂等,西医上常采用广谱抗菌药物进行治疗,长期使用易引起阴道菌群失调、机体免疫力下降[5-8].
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