血清人附睾蛋白4联合CA125对子宫内膜癌早期诊断及子宫外转移的临床价值

Diet Health（2018）

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Abstract

目的:评估术前血清CA125及HE4联合检测在子宫内膜癌(EC)的早期诊断与子宫外转移的临床价值.方法:连续入选150例EC患者术前的血清CA125及HE4水平,分析CA125及HE4与EC临床病理参数关系.结果:CA125、HE4单项检测的ROC-AUC值分别为0.636和0.760,联合检测为0.809,联合检测的ROC-AUC最大,差异均有统计学意义(P<0.01).EC患者血清CA125和HE4水平与临床分期、分化程度及有无子宫外转移有关,差异有统计学意义(P<0.01).结论:血清CA125及HE4联合检验对EC的早期诊断及子宫外转移的预测较单项检测更有优势.

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