葛根注射液急性毒性研究
Medical Diet and Health(2020)
Abstract
目的:考察葛根注射液对小鼠和大鼠的急性毒性.方法:对小鼠和大鼠进行了静脉给药和腹腔给药的最大给药量实验,连续两周考察小鼠和大鼠的毒性反应.结果:在小鼠静脉、腹腔注射最大剂量200g/kg(相当于临床成人一日用量1200倍),大鼠静脉注射最大剂量80g/kg(相当于临床成人一日用量480倍)、腹腔静脉注射最大剂量120g/kg(相当于临床成人一日用量720倍)后未见异常情况发生.结论:葛根注射液静脉给药安全度较大.
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