长期吸入皮质激素对哮喘患儿肺功能的改善及安全性评价
Psychological Doctor(2016)
Abstract
目的:探讨长期持续雾化吸入布地奈德、氟替卡松对哮喘患儿肺功能的改善情况及安全性.方法:选择96例6 ~ 48个月的哮喘患儿分为2组;组一45例持续(6个月)吸入布地奈德、每日1~ 2mg,Bid;组二41例吸入氟替卡松,每日100mg,Bid.治疗前及治疗6个月后分别测定各项肺功能指标、血皮质醇及骨密度.结果:治疗6个月后,肺功能有明显改善,血皮质醇及骨密度无明显变化.结论:吸入布地奈德1 ~ 2mg,Bid,氟替卡松气雾剂每日100mg,Bid,6个月后,能改善哮喘患儿肺功能,降低气道高反应性,对患儿肾上皮质功能及骨密度未见显著影响.
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