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基于PDGF/Akt/P70s6k信号传导通路研究蛇葡萄素抗肝纤维化的作用机制

wf(2019)

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Abstract
研究蛇葡萄素有明显的抗肝纤维化作用,据发现,它不仅抑制HSC的增殖,而且还降低了胶原蛋白Ⅰ,Ⅲ,Ⅳ,TGF-β1和PDGF由HSC产生的内容.因此本文主要探讨蛇葡萄素通过调控PDGF/Akt/P70s6k信号传导通路抗肝纤维化的作用机制.
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