补气健脑通络汤对气虚血瘀证缺血性脑卒中恢复期运动障碍的改善
Chinese Journal of Experimental Traditional Medical Formulae(2016)
Abstract
目的:观察补气健脑通络汤联合针灸治疗缺血性脑卒中(气虚血瘀证)恢复期运动障碍的临床疗效及对血清S-100B蛋白(S-100B),同型半胱氨酸(Hcy)水平的影响.方法:将96例缺血性脑卒中患者采用随机按住院前后顺序分为针灸组和观察组各48例.两组均采用常规内科治疗和肢体康复训练;针灸组采用针刺治疗,3次/周;观察组在针灸组治疗的基础上服用补气健脑通络汤,1剂/d,常规早晚水煎内服.两组疗程均为8周.采用Brunstrom评价两组临床疗效;对两组治疗前后上、下肢肌力和运动功能(FMMS),日常生活活动(BI)指数,平衡能力(BBS)和步行能力进行评分;检测两组治疗前后血清S-100B和Hcy水平.结果:观察组临床总有效率为87.5%,针灸组为68.75%,观察组优于针灸组(P<0.05);治疗后观察组上、下肢肌力评分明显低于针灸组(P<0.01),FMMS评分明显高于针灸组(P<0.01);观察组治疗后BI和BBS评分显著高于针灸组(P<0.01),步行能力评分明显低于针灸组(P<0.01);观察组治疗后血清S-100B和Hcy水平低于针灸组,比较差异均有统计学意义(P<0.01).结论:在常规内科和肢体康复训练治疗的基础上,补气健脑汤联合针灸治疗缺血性脑卒中(气虚血瘀证)恢复期患者,能明显改善患者上、下肢肌张力和运动功能,提高日常生活活动能力,提高平衡能力和步行能力,同时降低了患者血清S-100B和Hcy水平.
MoreKey words
ischemic stroke,Buqi Jiannao Tongluo Tang,acupuncture,syndrome of blood stasis due to qi deficiency,motor function
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