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干黄茶乳剂对慢性牙周炎患者龈沟液中TNF-α、IL-6和IL-10水平的影响及疗效观察

World Chinese Medicine(2016)

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Abstract
目的:观察干黄茶乳剂对慢性牙周炎患者龈沟液中TNF-α、IL-6和IL-10水平的影响及其疗效.方法:慢性牙周炎患者82例随机分为治疗组(41例)和对照组(41例).2组患者均给予龈上洁治、龈下刮治和根面平整等常规牙周基础治疗.治疗组给予干黄茶乳剂注满牙周袋内,对照组给予等量复方碘甘油液.1次/周,连续6周治疗.观察2组患者治疗前后龈沟液中TNF-α、IL-6和IL-10水平变化,比较临床有效率.结果:治疗结束后,2组患者龈沟液中TNF-αα、IL-6水平均明显下降,IL-10水平明显升高(P<0.05或P<0.01),且治疗组下降或升高幅度较对照组更显著(P<0.05).治疗组临床总有效率为95.12%,明显优于对照组75.61% (P <0.05).结论:干黄茶乳剂局部治疗慢性牙周炎的效果良好,能够降低龈沟液中TNF-α、IL-6水平,提高IL-10水平,从而有效控制牙周组织炎性反应损伤,改善局部炎性反应状况.
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Key words
Chronic periodontitis,Ganhuangcha cream,Inflammatory factors,Curative effect
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