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丹参注射液对脑挫裂伤皮质微血管保护作用的研究

薛贵平,薄爱华,张辉,李卫东,董建峰

SHAANXI JOURNAL OF TRADITIONAL CHINESE MEDICINE（2005）

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Abstract
目的:为探讨脑挫伤后脑血管的超微改变及丹参对其治疗作用.方法:采用自由落体法复制大鼠脑挫伤动物模型,并于伤后腹腔注射丹参注射液对其进行治疗.结果:脑挫裂伤后1～4d脑血管内皮水肿,管腔狭窄或闭塞、血脑屏障破坏.治疗组内皮细胞水肿较轻,管腔平均直径较模型组大,胶质细胞损伤较轻.结论:丹参能减轻脑挫裂伤后微血管内皮损伤,使微血管口径恢复快,具有改善皮质微循环作用.
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