薏柏痛风丸治疗湿热痹阻型痛风性关节炎的临床疗效观察
Journal of Guangzhou University of Traditional Chinese Medicine(2017)
Abstract
[目的]观察薏柏痛风丸内服治疗痛风性关节炎(GA)湿热痹阻证患者的临床疗效.[方法]将116例痛风性关节炎患者随机分为治疗组62例和对照组54例.治疗组给予薏柏痛风丸治疗,对照组急性期给予口服秋水仙碱和碳酸氢钠片治疗,缓解期给予苯溴马隆片治疗.以12周为1个疗程,观察2组临床疗效,比较2组治疗前后血中C反应蛋白(CRP)、 白细胞计数(WBC)、 血尿酸(UA)水平的变化情况.[结果](1)治疗组和对照组的总有效率分别为93.55%和83.33%,治疗组疗效优于对照组,差异有统计学意义(P<0.05).(2)治疗后,2组患者的中医证候积分均较治疗前明显降低(P<0.05),且治疗组的降低作用优于对照组(P<0.05).(3)治疗后,2组患者血中CRP、WBC、UA水平均有明显改善(P<0.05),且治疗组在改善CRP方面优于对照组(P<0.05),而在改善WBC、UA方面差异无统计学意义(P>0.05).[结论]薏柏痛风丸能有效改善湿热痹阻型痛风性关节炎患者的中医证候,迅速降低CRP水平,临床疗效显著.
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Key words
gouty arthritis,Yibai Tongfeng Pills,damp-heat obstruction,academic inheritance from famous specialists in traditional Chinese medicine
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