多指标综合评分法优选补正续骨颗粒最佳提取工艺

Journal of Changchun University of Traditional Chinese Medicine(2015)

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Abstract
目的:优选补正续骨颗粒的提取工艺。方法采用 L9(34)正交试验法,以出膏率为考察指标,优选最佳水提取工艺,以川续断皂苷Ⅵ与柚皮苷总含量及出膏率综合评分为评价指标,优选最佳乙醇提取工艺。结果最佳水提取工艺为加6倍量水,提取2次,每次提取1 h。最佳乙醇提取工艺为加6倍量60%乙醇,提取3次,每次2 h。结论优选的提工艺稳定可行,适用于补正续骨颗粒的工业化生产。
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Key words
Buzheng Xugu granules,asperosaponin,naringin,orthogonal experimental design
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