养精种玉汤辅以体外受精-胚胎移植对子宫内膜容受性的影响
China Journal of Chinese Medicine(2017)
Abstract
目的:观察养精种玉汤辅以体外受精-胚胎移植技术对子宫内膜容受性的影响.方法:将78例患者随机分为治疗组(39例)和对照组(39例),治疗组于应用促性腺激素释放激素激动剂(gonadotropin-releasing hormone agonist,GnRH-a)降调节时加服养精种玉汤,每日1剂,至HCG日停药.对照组采用标准方案治疗不加用中药.观察两组患者肾阴虚证候积分、子宫内膜厚度及形态、HCG日雌激素和孕激素水平、受精率及妊娠率.结果:治疗后治疗组患者肾阴虚证候积分改善情况与对照组比较,差异有统计学意义(P<0.05);治疗组治疗后内膜厚度大于治疗前,且与对照组比较,差异有统计学意义(P<0.05);两组患者HCG日雌激素、孕激素水平以及受精率比较,差异无统计学意义(P>0.05);治疗组妊娠率高于对照组,差异有统计学意义(P<0.05).结论:养精种玉汤可明显增加子宫内膜厚度,改善子宫内膜容受性,提高妊娠率.
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Key words
Yangjing Zhongyu Tang,in vitro fertilization and embryo transfer,TCM therapy,combination of traditional Chinese and Western medicine
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