血同型半胱氨酸在2型糖尿病肾病中的作用观察
JOURNAL OF ZHEJIANG COLLEGE OF TRADITIONAL CHINESE MEDICINE（2005）
Abstract
目的:探讨血浆总同型半胱氨酸水平(Hcy)与2型糖尿病肾病的关系.方法:应用高效液相色谱仪和荧光检测器测定39例2型糖尿病肾病变组和32例2型糖尿病无肾病变组的血浆总Hcy水平.并对糖尿病肾病患者应用胰岛素治疗4周后复查血浆总Hcy.结果:2型糖尿病肾病变组血浆Hcy,明显高于无肾病变组,胰岛素治疗4周后无明显改变.Logistic回归分析提示高Hcy是糖尿病肾病的独立危险因子.结论:2型糖尿病肾病变组血浆Hcy明显高于2型糖尿病无肾病变组,胰岛素治疗不能降低2型糖尿病肾病变组血浆Hcy.高Hcy是糖尿病肾病的独立危险因子.
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