参附注射液对帕金森病患者血压节律的影响
Guiding Journal of Traditional Chinese Medicine and Pharmacology（2016）
Abstract
目的:研究参附注射液对帕金森病(PD)患者血压节律异常的干预作用.方法:采用参附注射液治疗帕金森病(PD)血压节律异常患者20例,观察治疗前后患者血压的变化,用无创性携带式动态血压监测仪行24 h动态血压监测.结果:治疗前6例PD患者呈非杓型血压,反杓型12例,超杓型1例;经参附注射液治疗后,7例血压节律异常的患者转变为杓型血压.治疗后24 h平均血压变异系数、日间平均血压变异系数、夜间平均血压变异系数较治疗前降低(P＜0.05).治疗前后患者卧位收缩压和舒张压变化差异均无统计学意义(P＞0.05).结论:参附注射液对PD患者血压具有双向调节作用,可以稳定PD患者血压,改善PD患者血压节律异常.
MoreKey words
Parkinson disease,abnormal rhythm of blood pressure,24 hours ambulatory blood pressure monitoring,blood pressure coefficient of variation,Shenfu injection
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