二至丸对D-半乳糖致衰老模型大鼠行为学与脑组织NO含量及NOS活性的影响
Guiding Journal of Traditional Chinese Medicine and Pharmacology(2015)
Abstract
目的:观察二至丸对D-半乳糖致衰老模型大鼠学习记忆能力及脑组织中NO含量及NOS活性的影响.方法:采用D-半乳糖制造大鼠亚急性衰老模型.实验组分别灌胃不同浓度的二至丸及维生素E.用Morris水迷宫测定大鼠学习记忆能力,同时测定各组大鼠脑组织NO含量、NOS活性.结果:二至丸各治疗组均能提高衰老大鼠学习记忆能力、降低脑组织NO含量和NOS活性,且有剂量依赖型趋势.结论:二至丸能一定程度上提高D-半乳糖致衰老模型大鼠学习记忆能力,其机制可能与降低脑组织NO含量和NOS活性有关.
MoreKey words
Erzhi Wan,behavioristics,NO/NOS,mice,senility
AI Read Science
Must-Reading Tree
Example
![](https://originalfileserver.aminer.cn/sys/aminer/pubs/mrt_preview.jpeg)
Generate MRT to find the research sequence of this paper
Chat Paper
Summary is being generated by the instructions you defined