三七总皂苷的药理研究进展
Hunan Journal of Traditional Chinese Medicine(2019)
Abstract
三七是五加科人参属植物三七[Panax notoginseng(Burk.)F.H.Chen]的干燥根及根茎,具有化瘀止血、消肿止痛等功效,在传统中药中作为一种活血化瘀类药品而被广泛应用.三七总皂苷(panax notoginseng saponins,PNS)是三七的有效提取成分,其主要成分包括多种皂苷单体Rb1、Rg1、Re、Rd及三七皂苷R1等[1-2].PNS在心脑血管系统疾病、肿瘤、器官间质性疾病等方面有广泛的应用.它的临床使用制剂主要有血塞通、血栓通注射液及冻干粉针剂、路路通注射液、络泰粉针剂,还有口服制剂、水凝胶透皮贴剂、鼻腔粉雾剂和混悬凝胶剂等[3].
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