马钱子胶囊治疗硼替佐米引起周围神经病变的临床研究
Heilongjiang Journal of Traditional Chinese Medicine（2015）
Abstract
目的:观察马钱子胶囊治疗硼替佐米引起周围神经病变(bortezomib-induced peripheral neuropathy,BIPN)的疗效.方法:14例经弥可保、TTFD、氨磷汀等药物治疗无效的患者,予马钱子胶囊口服治疗,观察治疗前后的疗效、神经毒性评分、神经痛分级、中医症候积分及肌电图神经传导速度.结果:治疗后神经毒性评分、神经痛分级、中医症候积分降低(△P＜0.05),神经传导速度增加(△P＜0.05).结论:马钱子胶囊治疗硼替佐米引起周围神经病变临床疗效明确.
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