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13例前列腺导管腺癌临床病理分析

International Journal of Pathology and Clinical Medicine(2015)

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Abstract
目的:探讨前列腺导管腺癌的临床及病理组织学特征。方法:对13例前列腺导管腺癌进行光镜观察、免疫组织化学标记,鉴别诊断。结果:混合腺泡腺癌的导管腺癌最多见,占61.35%,大多发生于前列腺中央部,占76.92%,镜下呈乳头状、筛状或实性腺样排列,肿瘤细胞呈高柱状,胞浆丰富,嗜双色性,细胞异型性明显,大部分肿瘤细胞可见核仁。免疫组织化学标记PSA及AR均阳性13例,P504s阳性12例,P63及34βE12阳性1例,Ki-67增殖指数5%~80%。结论:前列腺导管腺癌与普通型腺癌相比,临床及病理特征均有差异,且需与高级别PIN、尿路上皮癌累及前列腺及尿道乳头状腺瘤相鉴别。
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Key words
prostate neoplsms ductal adenocarcinoma,clinicopathological,immunohistochemistry,diferential diagnosis
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