糖尿病大鼠孤束核的形态学变化

Chinese Journal of Anatomy(2015)

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Abstract
目的:探讨糖尿病对大鼠孤束核形态学的影响.方法:建立糖尿病大鼠模型,用多聚甲醛原位灌注固定后,取其孤束核部位,分别在光镜和电镜下观察其形态学变化.结果:与对照组相比,糖尿病大鼠孤束核部位神经元细胞排列紊乱,胞质密度降低,部分神经元线粒体出现空泡状改变、嵴断裂,并有髓鞘分裂现象.结论:糖尿病可导致大鼠孤束核部位神经元的形态学改变.
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Key words
nucleus tractus solitarius,diabetic mellitus,arterial baroreflex,carotid sinus baroreceptor reflex
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