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肥厚型心肌病分子研究进展

Huajie Huang,Fu Xiong,Hua Zheng

International Journal of Genetics（2017）

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Abstract
肥厚型心肌病(hypertrophic cardiomyopathy,HCM)是常见遗传性心血管疾病,其发病率可达1/500.该病是目前年轻运动员心源性猝死的重要病因,可在各个年龄段发病,其中50％～70％HCM由基因突变所致.近年来,HCM的分子研究已取得较大进展,本文就HCM相关的主要致病基因及其分子机制作一综述.
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Key words
Hypertrophic cardiomyopathy,Gene,Molecular mechanism
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