PDCD5基因功能的研究进展
International Journal of Genetics（2015）
Abstract
PDCD5是重要的促凋亡基因,还有抑制炎症的作用.PDCD5的异常表达与多种人类疾病如肿瘤,退行性变和自身免疫病等相关.本文综述了PDCD5促进凋亡和抑制肿瘤的机制、PDCD5在肿瘤基因治疗中的应用、应用转基因小鼠研究PDCD5的功能以及应用PDCD5治疗人类疾病的方向.
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Key words
PDCD5,Apoptosis,Inflammation,Cancer,Gene therapy
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