细胞分裂周期蛋白7的研究进展

International Journal of Genetics(2014)

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Abstract
细胞分裂周期蛋白7(CDC7)是DNA复制起始过程中一个重要的蛋白激酶,它与调节亚基DBF4组成丝氨酸/苏氨酸激酶复合体DDK,该复合体在DNA复制中发挥重要作用.本文就CDC7的起源、调控、功能、相关疾病及其抑制剂作一综述.
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Key words
CDC7,DBF4,MCM,PHA-767491
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