我国NICU卒中相关性肺炎危险因素的Meta分析
Chinese Nursing Research(2018)
Abstract
[目的]系统分析我国神经重症监护病房(NICU)卒中相关性肺炎发生的主要危险因素.[方法]检索中国生物医学文献数据库(CBM)、中国知网(CNKI)、维普、万方、PubMed,Embase数据库及Cochrane图书馆中有关我国NICU卒中相关性肺炎危险因素的文献,提取数据并采用Stata13.0软件进行Meta分析.[结果]共纳入11篇文献,我国NICU卒中相关性肺炎各独立危险因素合并OR值及其95% CI分别为:留置鼻饲管1.783(1.535,2.031);使用抑酸药物1.154(0.833,1.476);气管切开0.846(0.311, 1.380);机械通气0.561(0.428,0.695);预防性使用抗生素0.953(0.573,1.333);吞咽障碍2.131(1.628,2.634);意识障碍2.056 (1.436,2.676);延髓性麻痹1.613(0.814,2.411);肺部疾病史1.029(0.581,1.478);糖尿病史0.687(0.397,0.976);吸烟史0.939 (0.459,1.419).[结论]留置鼻饲管、使用抑酸药物、气管切开、机械通气、预防性使用抗生素、吞咽障碍、意识障碍、延髓性麻痹、肺部疾病史、糖尿病史、吸烟史为我国NICU卒中相关性肺炎的主要危险因素.
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Key words
neurological intensive care unit,stroke-associated pneumonia,stroke,pneumonia,risk factors,meta-analysis
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