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CFW荧光染色法检测疑似真菌感染的临床应用评价

Wenjing HE,Zhiqin GAO,Jian CHEN,Hongjin REN,Hong YANG,Qing CAI,Lianjuan YANG

Laboratory Medicine（2018）

Cited 1|Views17
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Abstract
目的 探讨荧光染色剂Calcofluor White(CFW)在真菌感染诊断中的临床应用价值,并与传统KOH湿片镜检法及真菌培养法进行比较,寻找更有效的真菌检测方法.方法 选取临床155例疑似真菌感染的患者,采用KOH湿片镜检法、CFW荧光染色法和真菌培养法进行检测.结果 CFW荧光染色法阳性率(85.8%)最高,KOH湿片镜检法阳性率(76.1%)次之,二者差异有统计学意义(χ2=14.45,P<0.05),真菌培养法阳性率(71.0%)最低.结论 CFW荧光染色法可显著提高真菌检测的阳性率,是一种有效的真菌检测方法.
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Key words
Fluorescent dye Calcofluor White,KOH,Fungal culturing
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