血清AFP,CEA,CA-199与TAP在肝癌诊断中的应用价值
Journal of Modern Laboratory Medicine(2015)
Abstract
目的 探讨血清甲胎蛋白(AFP),癌胚抗原(CEA),糖链抗原199(CA-199)与糖链糖蛋白(TAP)在肝癌诊断中的应用价值.方法 收集69例肝癌患者为研究对象,比较各肿瘤标记物(TM)的敏感度、特异度及阳性率等指标.结果 肝癌确诊患者中,TAP,CEA,AFP,CA-199及联合检测敏感度分别为88.40%,40.60%,53.6%,34.80%和95.60%;阳性率分别为68.40%,40.54%,46.84%,34.23%和75.67%.四项肿瘤标记物联合检测敏感度(95.60%)和阳性率(75.67%)明显高于其他各单项检测指标,特别是在继发性肝癌中,联合检测起到明显弥补作用.结论 四项肿瘤标记物联合检测优于AFP,CEA,CA-199和TAP各单项检测,是一个很好的肝癌筛查方法.
MoreKey words
TAP,AFP,CEA,CA-199,liver cancer
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