血清CA125在慢性心力衰竭诊断中的应用价值
Zhejiang Clinical Medical Journal(2017)
Abstract
目的 探讨慢性心力衰竭患者中血清CA125和BNP、CRP、射血分数、左房内径、左室舒张末内径的相关性.方法 选择慢性心力衰竭患者113例,根据血清CA125水平分为CA125正常组(CA125<35U/ml)和CA125升高组(CA125≥35U/ml),入院后检测血清CA125、BNP、CRP水平,并完善心脏彩超检查,记录射血分数、左房内径、左室舒张末内径.结果 两组左房内径、左室舒张末内径、左心室射血分数、BNP差异有统计学意义.心力衰竭合并胸腔积液组CA125水平显著高于心力衰竭未合并胸腔积液组.CA125水平与BNP呈正相关(r=0.330,P=0.000);CA125水平与LVEF、CRP无相关性.结论 CA125水平可作为慢性心力衰竭诊断的一项重要指标.
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Key words
Chronic heart failure,CA125,BNP
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