MRI动态增强扫描及扩散加权成像鉴别乳腺良恶性病变的价值
Modern Medical Imagelogy(2017)
Abstract
目的:研究MRI动态增强及DWI鉴别乳腺良恶性病变的半定量及定量价值.方法:分析60例经病理证实的乳腺病变患者的MRI动态增强及DWI,研究TIC、早期强化率及ADC值的诊断效能,并联合三种指标制定综合评分系统.结果:恶性病灶TIC多呈流出型,良性多呈流入型,TIC鉴别良恶性病变的敏感度为0.851,特异度为0.766,AUC为0.781.增强第1周期早期强化率(61.5%)的敏感度为0.882,特异度为0.816,AUC为0.802;第2周期早期强化率(92.3%)的敏感度为0.891,特异度为0.924,AUC为0.895.良恶性病灶ADC值有统计学差异,ADC值1.135×10-3mm2/s为阈值的敏感度为0.852,特异度为0.734,AUC为0.771.良性病灶综合评分明显低于恶性病灶,其评分与病理结果有明显相关性,r值=0.89,P<0.05.结论:增强第2周期早期强化率是鉴别乳腺良恶性病变最有效的指标,联合三种指标综合评分能够明显提高鉴别诊断的准确率.
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