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桥本甲状腺炎合并甲状腺癌的临床病理研究

杨践,何永刚,蔡伟耀,李宏为

JOURNAL OF DIAGNOSTICS CONCEPTS & PRACTICE（2005）

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Abstract
目的:探讨桥本甲状腺炎(HT)与甲状腺乳头状癌(PTC)的关系.方法:单纯HT 73例,HT合并PTC 23例,分析两者的临床表现、病理组织学表现,并作酪氨酸激酶受体(RET)免疫组化染色.结果:HT临床表现多样化,部分表现为结节状,合并的甲状腺癌均为乳头状癌,且微小癌占多数.50%HT病变对于RET染色存在局灶性阳性反应.结论:HT病变组织中不同程度地存在与PTC相同的肿瘤基因,HT合并的PTC可能与HT有关.
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Key words
thyroiditis,hashimoto,carcinoma
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