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卷曲霉素治疗耐药结核病作用机制、毒副作用及耐药机制的研究进展

Qiuyang LI,Ling CHEN

Practical Journal of Cardiac Cerebral Pneumal and Vascular Disease(2019)

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Abstract
耐药结核病的出现给全球范围内结核病防控工作带来前所未有的挑战.耐药结核病需采用二线抗结核药物治疗,而卷曲霉素属注射类药物,是治疗耐药结核病的核心二线抗结核药物之一,但近年来卷曲霉素因耳毒性等毒副作用而在临床应用受限.本文对卷曲霉素治疗耐药结核病的作用机制、毒副作用及耐药机制等进行了综述,以期提高临床对卷曲霉素的认识并合理使用卷曲霉素.
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