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地特胰岛素用于治疗口服降糖药控制不佳的2型糖尿病患者疗效观察

Ze-hua ZHOU,Rong XIAO

CHINESE JOURNAL OF DIABETES（2011）

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Abstract
目的 观察地特胰岛素对口服降糖药(OAD)控制不佳的2型糖尿病(T2DM)患者临床疗效.方法 33例OAD血糖控制不佳的T2DM患者,加用地特胰岛素每日睡前皮下注射,共24周.观察用药前后FBG、2hBG、HbA1 c、BMI等的变化.结果 治疗后T2DM患者FBG、2hBG、Hb A1 c均明显下降(P<0.01).日间低血糖发生率9.1%,无夜间症状性低血糖发生,体重无明显增加.结论 CAD控制不佳的T2DM患者加用地特胰岛素可有效控制血糖,低血糖发生率低,体重增加不明显.
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Key words
Diabetes mellitus,type 2,Insulin detemir,Oral antidiabetic drugs
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